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Chemical Biology, Omics Technologies, & Neurochemistry 

Our lab uses chemical biology methods to investigate protein damages and protein clearance in aging cells and neurodegenerative disorders, focusing on the following topics:

 

1) Synaptic pathology in Alzheimer's disease, investigated by fluorescence and super-resolution imaging, flow cytometry, next-generation sequencing, and LC-MS (proteomics and metabolomics).

2)  Immunotherapy against tau oligomers in Alzheimer's disease

3) Method development in proteomics and metabolomics, mostly based on LC-MS.

Professor Hwan-Ching Tai has recently received the "Periodic Table of Younger Chemists--Phosphorous Award." It is a special award given by IUPAC in celebration of 2019, the International Year of the Periodic Table, designated by the United Nations. 

Principal investigator:

 

Dr. Hwan-Ching Tai (Bruce)

Associate Professor of Chemistry.

Ph.D. California Institute of Technology, 2009

台大化學系

戴桓青副教授

email: hctai at ntu.edu.tw  

PDF files of our papers are available for download.

Here is a link to our 

Google Scholar Profile 

Our research interests also include antique Italian violins by Stradivari and Guarneri. Our focus is wood manipulation, wood aging, and acoustics. Our findings have been reported by The New York Times and BBC Radio.   

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